Talk:Organ transplantation

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This article was the subject of a Wiki Education Foundation-supported course assignment, between 21 January 2019 and 16 May 2019. Further details are available on the course page. Student editor(s): Siqisong16.

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Organ gifting; merge

I suggest merging the new article organ gifting to here. There seems too great an overlap for two standalone articles. What do others think? --John (talk) 15:05, 14 May 2010 (UTC)

Organ transplantation covers a wide area of which Organ donation, Organ harvesting, Organ trade, Religious views on organ donation and Organ gifting are a part. Organ gifting deals with medical issues surrounding donation - it is a distinct area, so a merge is not appropriate. As part of a general tidy up of articles relating to organ transplantaion it might be worth considering how much of the content of Organ gifting should be summarised in either this article (Organ transplantation) or the Organ donation article. SilkTork *^YES! 17:35, 5 July 2010 (UTC)

Gonad transplant

I removed the following paragraph, as it seems dubious.

Transplant of a single gonad (testis) from a living donor was carried out in early July 1926 in Zaječar, Serbia, by a Russian emigré surgeon Dr. Peter Vasil'evič Kolesnikov. The donor was a convicted murderer, one Ilija Krajan, whose death sentence was commuted to 20 years imprisonment and he was led to believe that it was done because he had donated his testis to an elderly medical doctor. Both the donor and the receiver survived, but charges were brought in a court of law by the public prosecutor against Dr. Kolesnikov, not for performing the operation, but for lying to the donor. (v. Timočki medicinski glasnik, Vol.29 (2004) #2, p. 115-117 ISSN 0350-2899 article in Serbian)

Although the ISSN checks out, I could not find any relevant Google hits (web, books, journals) for "Ilija Krajan" or "Peter Kolesnikov" and the web link that's given is dead. You'd think that if someone successfully carried out an organ transplant in 1926, it would be documented somewhere. howcheng {chat} 03:05, 22 December 2010 (UTC)

_________________

It seems you couldn't find because you didn't look. The name of the medical hounral is given above as "Timočki medicinski glasnik" and the year, vol. and pp. are given too. The only reason that the link appeared broken to you is because the .yu domain of Federal Republic of Yugoslavia had been discontinued and they use the .rs domain for Serbia now.

The page is on: http://tmg.org.rs/v290210.htm, and for the poor monolinguals out there, there's Google Translate: http://translate.google.com.hk/translate?hl=en&ie=UTF8&prev=_t&sl=sr&tl=en&u=http://tmg.org.rs/v290210.htm — Preceding unsigned comment added by 113.68.101.167 (talk) 16:13, 17 June 2013 (UTC)

Downsides of organ transplants

There should be some mention of the many downsides of organ transplantation.

Fix dead links & link to other wikipedia page

For the references that are currently listed as dead links under the section titled, "Forced donation" http://www.wma.net/en/40news/20archives/2006/2006_04/index.html & https://dafoh.org/Matas_speech.php might be more useful resources. Also for more detailed information on the organ donation laws in China I suggest there be a link to the wikipedia page titled, Organ transplantation in the People's Republic of China in the section titled, "Organ transplant laws." Naf24 (talk) 18:13, 31 August 2011 (UTC)

Regrettably censored article.

The "Forced Donation" section is totally watered down. It fails to mention by name the single most outrageous violent organ transplant incident, the "Yellow House" scandal, where kosovan alban rebels culled 300 caged serbian women, children and POWs and shipped their organs to turkish private clinics for transplant into certain foreigners.

The EU comissioner lady quit her position after french, german, US and Vatican heads all told her to stop investigating this case of genocide due to ineffable Middle East connections. The serbian state security agency has sworn to effect revenge on Hasim Tachi, the alban honcho who was responsible for this heinous crime. 82.131.210.163 (talk) 16:56, 8 December 2011 (UTC)

Section Types of donor

This section seems out of date, factually incorrect, contradicts other articles and has a US bias. Is there anyone who takes an interest in organ donation who would be able to update this section? Mike 16:08, 16 December 2011 (UTC)

Suggestion of a stub or related article

In regards to expanding on this section, one should consider a stub about animal replacement based organs, such as the Vacanti mouse. The idea of growing replacement organs, limbs, or tissue from other animals was an idea that circulated in the late 90's but hasn't been expanded. Should one be included?

vguyver *^YES! 23:27, 5 February 2012 (UTC) — Preceding unsigned comment added by 67.81.204.31 (talk)

Ethics - cost-effectiveness

Given that in the United States, a kidney transplant may demand $100,000, a liver $250,000, and a heart $860,000, what is the cost-effectiveness of such operations, compared to other medical interventions, like vaccines, preventive care, ... [QUALY] stats available? Let's add that to the article...--Elvey (talk) 21:34, 10 May 2012 (UTC)

Dayton, J. D., Kanter, K. R., Vincent, R. N., & Mahle, W. T. (2006). Cost-effectiveness of pediatric heart transplantation. The Journal of Heart and Lung Transplantation, 25(4), 409–415. doi:10.1016/j.healun.2005.11.443 65.166.89.2 (talk) 16:10, 5 April 2013 (UTC)

And http://www.organdonation.nhs.uk/newsroom/fact_sheets/cost_effectiveness_of_transplantation.asp about kidney transplants that are described as "highly cost-effective". Sjö (talk) 08:22, 22 May 2013 (UTC)

First ovarian transplant

The article mentions Dr P Mhatre as having done the first ovarian transplant at Wadia Hospital Bombay in 2005. However, there was a news article in 2002 that talked about Dr Mhatre having performed it at Kothari Hospital. It also said that the operation was first done in China at Zhejiang Medical Science University in March of that year. Here is a link to the article: http://articles.timesofindia.indiatimes.com/2002-05-25/mumbai/27123486_1_ovary-egg-donors-city-doctors ````uttamsirur 28/9/2012 — Preceding unsigned comment added by Uttamsirur (talk • contribs) 05:15, 28 September 2012 (UTC)

Article name

'Transplant surgery' redirects here; but this article discusses hands, arms, legs, faces and corneas, none of which are organs. I think the former would be a more appropriate location for this content. Andy Mabbett (Pigsonthewing); Talk to Andy; Andy's edits 18:14, 4 January 2013 (UTC)

Moved here as not refs

Extended content

collective (2008). "Organ trafficking and transplant tourism and commercialism: the Declaration of Istanbul" (PDF). The Lancet. 372 (9632): 5–6. doi:10.1016/S0140-6736(08)60967-8. PMID 18603141. Appel, Jacob M.; Fox, Mark D. (2005). "Organ Solicitation on the Internet: Every Man for Himself?". Hastings Center Report. 35 (3): 14–15. doi:10.1353/hcr.2005.0052. PMID 16092393. Budiani-Saberi, Debra A.; Delmonico, Francis L. (2008). "Organ Trafficking and Transplant Tourism: A Commentary on the Global Realities" (PDF). American Journal of Transplantation. 8 (5): 925–929. doi:10.1111/j.1600-6143.2008.02200.x. PMID 18416734. Caplan, Arthur L.; Coelho, Daniel H., eds. (1998). The Ethics of Organ Transplants: The Current Debate. New York: Prometheus Books. ISBN 1-57392-224-2. Cherry, Mark J. (2005). Kidney For Sale By Owner: Human Organs, Transplantation, And The Market. Washington, D.C: Georgetown University Press. ISBN 1-58901-040-X. Cooper, David K.C.; Lanza, Robert P. (2000). Xeno: The Promise of Transplanting Animal Organs into Humans. Oxford: Oxford University Press. p. 304. ISBN 978-0-19-512833-8. {{cite book}}: External link in |deadurl= (help); Unknown parameter |deadurl= ignored (|url-status= suggested) (help) Danovitch, Gabriel M.; Delmonico, Francis L. (2008). "The prohibition of kidney sales and organ markets should remain". Current Opinion in Organ Transplantation. 13 (4): 386–394. doi:10.1097/MOT.0b013e3283097476. PMID 18685334. Finn, Robert (2000). Organ Transplants: Making the Most of Your Gift of Life. Patient Center Guides. ISBN 1-56592-634-X. Gruessner, Rainer; Benedetti, Enrico (2008). Living Donor Organ Transplantation. New York: McGraw-Hill. p. 791. ISBN 978-0-07-145549-7. Hu W, Lu J, Zhang L; et al. (October 2006). "A preliminary report of penile transplantation". European Urology. 50 (4): 851–3. doi:10.1016/j.eururo.2006.07.026. PMID 16930814. {{cite journal}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link) Köchler, Hans, ed. (2001). Transplantationsmedizin und personale Identität. Medizinische, ethische, rechtliche und theologische Aspekte der Organverpflanzung (in German). Frankfurt: Peter Lang. ISBN 3-631-38363-0. {{cite book}}: Unknown parameter |trans_title= ignored (|trans-title= suggested) (help) Lock, Margaret M. (2002). Twice Dead: Organ Transplants and the Reinvention of Death. Berkeley: University of California Press. ISBN 0-520-22605-4. McLean, Shella A.M.; Williamson, Laura (2005). Xenotransplantation: Law and Ethics. Aldershot: Ashgate Publishing. p. 290. ISBN 0-7546-2379-3. Morris PJ (December 2004). "Transplantation—a medical miracle of the 20th century". New England Journal of Medicine. 351 (26): 2678–80. doi:10.1056/NEJMp048256. PMID 15616201. Sayeed, Sadath A. (2009). "Teaching ethics and trading organs". Indian Journal of Medical Ethics. 6 (1): 25–27. PMID 19241951. Shimazono, Yosuke (2007). "The state of the international organ trade: a provisional picture based on integration of available information". Bulletin of the World Health Organization. 85 (12): 901–980. doi:10.2471/BLT.06.039370. PMC 2636295. PMID 18278256. Taylor, James S. (2005). Stakes and Kidneys: Why Markets in Human Body parts are Morally Imperative. Aldershot, Hants, England: Ashgate. ISBN 0-7546-4109-0. Trzepacz, Paula T.; DiMartini, Andrea F. (2000). The Transplant Patient: Biological, Psychiatric, and Ethical Issues in Organ Transplantation. Cambridge / New York: Cambridge University Press. p. 311. ISBN 0-521-55354-7.

Doc James (talk · contribs · email) 23:13, 2 December 2014 (UTC)

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additional reference on 'domino' transplant

After rare procedure, woman can hear her heart beat in another, Stanford Medicine News Center, Sara Wykes, March 29, 2016.

' . . . Domino transplantation of a heart-lung and heart does, however, benefit two people. A highly unusual procedure, it has only been performed at Stanford eight times before, last in 1994.

'For Griffin, who has cystic fibrosis, receiving new lungs was critical. Her lung capacity had diminished so much that she was on oxygen full time, unable to do much at all. She had so little energy that she couldn’t get through a shower without sitting down to rest.

'Her heart, however, was still functioning well. “Her heart was an innocent bystander pushed out of its normal position in the middle of the lungs as her right lung shrank and the left one expanded,” said Joseph Woo, MD, a cardiothoracic surgeon at Stanford Health Care who oversaw and coordinated the surgical teams that conducted the domino procedure. That displacement made a heart-lung transplant the only viable option for Griffin, . . . '

Don't know if our article currently includes this as potential reason for domino transplant, going to check. And the broader human context discussed by this piece might also make it worth including. FriendlyRiverOtter (talk) 20:33, 30 December 2016 (UTC)

good article on messy and complicated real world details

Heart of the matter, The Guardian [UK], Simon Garfield, April 6, 2008.

"In the last week of October 2007, the patients on the heart transplant waiting list at Papworth Hospital received disturbing news in the mail. Papworth, on the outskirts of Cambridge, the venue for the first successful heart transplant in the UK, in 1979, had hit a bad patch. Between January and September 2007, the hospital had carried out 20 heart transplants, and seven patients had died within 30 days. In addition, another patient who had received a new heart in October was in a critical condition and would fail to make it. The letter to patients on the waiting list explained that all further operations would be suspended until the reasons for what was a dramatic increase had been examined. . . "

" . . . When the Healthcare Commission delivered, on 19 November, its findings into the eight deaths at Papworth, it made 12 recommendations. It noted the general quality of care at the transplant unit was good, but that there was room for improvement. The recommendations included: minimising the time the heart is left without blood supply during transportation; a careful review of the use of the solution which temporarily paralyses the organ's tissue during the transplant; changing the current arrangements in which the surgeon undertaking the transplant operation is also responsible for post-operative care; an immediate investigation into any new deaths, initially involving external review; and finally, a suggestion that all future patients contemplating heart transplants are properly informed about Papworth's recent increase in mortality rates and the subsequent attempts to improve them. . . "

" . . . As Tsui [Steven Tsui, head of transplant team at Papworth] says, 'Conventionally we would say if people's life expectancy was a year or less we would consider them a candidate for a heart transplant. But we also have to manage expectations. If we know that in an average year we will do 30 heart transplants, there is no point putting 60 people on our waiting list, because we know half of them will die and it's not right to give them false hope.' In other words, there may be thousands of patients who would materially benefit from a transplant if only the resources and organs were available. . . "

" . . . The laws governing seatbelts, motorcycle helmets and speed, coupled with the tighter punishments for drink-driving and safer cars, have ensured that fewer young people kill themselves in accidents. Health and safety regulations have resulted in fewer fatal accidents at work. And improvements in drugs in recent years for those who have suffered a brain haemorrhage or a stroke have also had a direct result on donor hearts. . . "

" . . . Tsui believes there is an easy way to reduce the mortality rate at his hospital - by turning down high-risk operations. 'But that is doing a disservice to those patients. If they have a 10 or 15 per cent risk of failure, they'll still be better off, because without it they're doomed. So there is a danger that the monitoring process may deny patients treatment that they would benefit from.' . . "

" . . . In 2002, Stephen Large, a transplant surgeon at Papworth, wrote a letter to the Lancet suggesting there might be a 'crisis' in his industry. Donor availability was only one problem, he argued, observing that there was also significant disorganisation and 'organ wastage'. He saw considerable disillusionment among the young trainees he worked with. . . "

Now somewhat dated at April 2008, but still some good info. FriendlyRiverOtter (talk) 20:07, 11 January 2017 (UTC)

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potentially good articles on lung tranplantation

History of Lung Transplantation, Turkish Thoracic Journal, Gül Dabak and Ömer Şenbaklavacı, April 2016.

History of lung transplantation (Review Article), Journal of Thoracic Disease, Federico Venuta, Dirk Van Raemdonck, Dec. 2017.

I'll try to take a look at these when I have some time. The example of Turkey might be particularly interesting. Please jump in and help if the topic interests you. FriendlyRiverOtter (talk) 17:33, 6 July 2018 (UTC)

Attribution

References copied from Organ transplantation#Allocation of organs to Derrick Morris See former article's history for a list of contributors. 7&6=thirteen (☎) 14:13, 20 April 2019 (UTC)

Lead's first sentence; Kidney transplants

Looking to expand the first sentence of the lead, as all organ transplant surgeries are not exclusively for the purpose of replac[ing] a damaged or missing organ. Obviously with kidney transplants, this is one surgery where (usually) an organ is not replaced, but rather the donor kidney acts to supplant the function of the other kidneys. I am not aware of other surgeries where this is the case, but this should be expounded on in the article: some transplants do not include the replacement of organs, re: kidneys. --PerpetuityGrat (talk) 17:59, 18 November 2021 (UTC)

Sources

Living organ transplant

I'm Ankit Sharma from gurgaon haryana. I'm 26 year old. My kidney are damage second time. I'm very upset . I want to finished my life . I have attority to donate my organs. Please contact me 8700164100 2409:4050:2D88:223B:F509:357D:ED67:BFB7 (talk) 18:02, 25 November 2021 (UTC)